This study compared five ways to remotely monitor the health and wellbeing of patients with multiple chronic conditions once they return home from the hospital after treatment for sepsis or lower respiratory tract infection.

Funded by:

Patient-Centered Outcomes Research Institute (PCORI®)

Funding Amount:

$4,416,351

Project Duration:

August 3, 2020 - September 30, 2026

Project Collaborators:

Wolff Center at UPMC

UPMC Community and Ambulatory Services

UPMC Clinical Analytics

University of Pittsburgh Department of Critical Care Medicine

Research Location:

This study takes place in 20 hospitals throughout western and central Pennsylvania.

Background

Having multiple chronic, or long-term, health problems can make it more likely that patients who’ve had an infection, such as pneumonia, return to the hospital after a hospital stay. Monitoring patients' health at home after they leave the hospital may keep them from having to return. Many hospitals monitor patients with a telephone call. A nurse calls patients two days after they leave the hospital to answer questions and check on medicines and follow-up care. But for patients with multiple chronic conditions, a single telephone call may not be enough.
In this study, the research team is compared different smart phone-based approaches to monitor patients at home for three months after hospitalization. The team wanted to learn which approaches keep patients from returning to the hospital.

See our clinicaltrials.gov and PCORI® descriptions for more details.

Healthcare Challenge

Nationally, hospital readmissions after sepsis and pneumonia are more common and more costly than readmissions due to heart failure, chronic obstructive pulmonary disease (COPD), or myocardial infarction. Research suggests that if identified early enough, the cause of many of these readmissions could be treated on an outpatient basis potentially allowing patients to stay out of the hospital and spend more time at home.

Goals

  • Maximize UPMC Health Plan member days spent at home by identifying the remote-patient monitoring (RPM) strategy that best identifies and treats post-discharge health issues before they cause a hospital readmission among patients with sepsis and lower respiratory tract infections.
  • Learn the facilitators, barriers, and contextual factors associated with RPM engagement, satisfaction, and effectiveness.

Implementation Approach

Population

UPMC Health Plan and traditional Medicare Fee-for-Service patients hospitalized with sepsis or lower respiratory tract infection (LRTI) and at medium- to high-risk of readmission who own a phone which they can use to participate in RPM.

Methodology

Structured Telephone Support: A nurse called the patient once within seven days after discharge to check in, help them understand their medicines, and make sure they get the care they need. - RPM Low: Questions focused on worsening infection. RPM High: Questions focused on worsening infection and worsening underlying heart and lung conditions. - Standard Team: RPM alerts were screened by a nurse-staffed call center. Nurses determined whether emergency care was needed. If not, nurses contacted the patient and/or the patient's PCP or specialist to coordinate care and ensure timely follow-up. - Enhanced Team: RPM alerts were screened by a nurse-staffed call center. Nurses determined whether emergency care is needed. If not, the call center alerted a multidisciplinary care team led by a certified registered nurse practitioner (CRNP). CRNPs, who operate in a palliative care role, have prescribing authority and can modify care plans. In addition to reacting to RPM triggers, team members (e.g., CRNP, social workers, nurses) met with the patient in-person or virtually in the week after discharge and at least twice more in the next 90 days, conducted assessments and a pharmacy review, developed care plans, and completed a POLST (physician orders for life-sustaining treatment) or an PA Advance Care Directive.

Participants must have access to a smart phone to be eligible for the study.

  • Structured Telephone Support: A nurse will call the patient once within seven days after discharge to check in, help them understand their medicines, and make sure they get the care they need.
  • RPM Low: Questions focused on worsening infection.
  • RPM High: Questions focused on worsening infection and worsening underlying heart and lung conditions.
  • Standard Team: RPM alerts are screened by a nurse-staffed call center. Nurses determine whether emergency care is needed. If not, nurses contact the patient and/or the patient's PCP or specialist to coordinate care and ensure timely follow-up. 
  • Enhanced Team: RPM alerts are screened by a nurse-staffed call center. Nurses determine whether emergency care is needed. If not, the call center alerts a multidisciplinary care team that is led by a certified registered nurse practitioner (CRNP). CRNPs, who operate in a palliative care role, have prescribing authority and can modify care plans. In addition to reacting to RPM triggers, team members (e.g., CRNP, social workers, nurses) meet with the patient in-person or virtually in the week after discharge and at least twice more in the next 90 days, conduct assessments and a pharmacy review, develop care plans, and complete a POLST (physician orders for life-sustaining treatment) or an PA Advance Care Directive.

Participants were asked to complete two surveys for the project - one immediately after they are discharged home from the hospital and one at 90 days. Participants reported on their physical function and quality of life with these surveys.

The intervention teams, participant PCPs, and participants completed qualitative interviews. Participants were asked to share about their satisfaction, value of the study, and if the study improved quality of life. The care team (intervention teams and PCPs) were invited to share about challenges and benefits to engaging and implementing the ACCOMPLISH Project.

The study design implementation was advised by patient-partners, a patient-partner study co-investigator, and an advisory board comprising health providers, patients, researchers, payers, policy makers, and community organizers/organizations.

Outcomes of Interest

The number of days patients spent at home during the 90 days after hospital discharge to home, and the effectiveness of each monitoring strategy considering additional patient factors such as comorbidities, living arrangements, age, gender, and socioeconomic status.

This project was funded through the Patient-Centered Outcomes Research Institute® (PCORI®) Award IHS-2019C1-16055. The views, statements, and opinions presented in this webpage are solely the responsibility of the author(s) and do not necessarily represent the views of PCORI®.